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KMID : 0861020060210030047
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Korea Journal of Herbology
2006 Volume.21 No. 3 p.47 ~ p.54
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Preventive effects of Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol
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Kim You-Chang
Kim Seong-Mo
Choi Hong-Sik
Park Ji-Ha
Seo Bu-Il
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Abstract
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Objectives : This study was performed to compare the preventive effect of water extracts from Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol.
Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. We measured the serum component in rat’s blood, body weight and weight of liver.
Results : 1. At first, we observed effects of Injinho-tang and Haninjinho-tang on hyperlipidemia induced by alcohol. Injinho-tang group showed significant decrease of triglyceride, body weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of total cholesterol, triglyceride in comparison with those of the control group. I 2. At second, we observed effects of Injinho-tang and Haninjinho-tang on liver damage induced by alcohol. lnjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase), ALP (alkaline phosphatase), liver weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase) in comparison with those of the control group.
Conclusion : Reviewing these experimental results, it appears that water extracts from Injinho-tang and Haninjinho-tang have pharmaceutical preventive efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.
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KEYWORD
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Injinho-tang, Haninjinho-tang, hyperlipidemia, liver damage, alcohol, Haninjin, Artemisiae iwayomogi Kitamura
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